Daidzein is an isoflavone found in soybeans. Regulates oxidative stress, angiogenesis, cell growth and apoptosis. Daidzein has antioxidant, antiestrogenic, and antiatherogenic properties. Provides protection against osteoporosis.
Daidzein has been used:
- as a control to assess fertility in rats
- to study its effects on ovarian cancer
- to stimulate antioxidant activity in vitro
25 mg in a polyethylene bottle
100 mg in a glass bottle
Packed under argon.
- Quality level: 200
- Biological source: synthetic
- Test: ≥98%
- Form: dust
- Mp: > 290 ° C
- Solubility: DMSO: 10 mg / ml
- Storage temperature: −20 ° C
- SMILES chain Oc1ccc (cc1) C2 = COc3cc (O) ccc3C2 = O
- InChI 1S / C15H10O4 / c16-10-3-1-9 (2-4-10) 13-8-19-14-7-11 (17) 5-6-12 (14) 15 (13) 18 / h1- 8.16-17H
- InChI key ZQSIJRDFPHDXIC-UHFFFAOYSA-N
Biochemical / Physiological Actions
The soy isoflavone daidzein protects against oxidative damage to liver cells induced by 7,12-dimethylbenzaanthracene (DMBA). Catalase and superoxide dismutase activity, down-regulated by DMBA, was restored by daidzein.
Daidzein is a phytoestrogen that is suggested to play a role in the prevention of hormone-induced cancers. Stops the cell cycle at G1 in Swiss 3T3 cells.
Features and Benefits
This compound is also offered as part of Sigma’s Library of Pharmacologically Active Compounds (LOPAC®1280), a biological annotation collection of high-quality, ready-to-test compounds. Click here to find out more.
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